Dna Computing Thesis

Dna Computing Thesis-27
During the '80s, when Adleman took on AIDS research in addition to mathematics, he found himself in a rare position for a computer scientist - he already knew how to do biological benchwork.He was able to synthesize strands of DNA, and splice and dice them to read the messages spelled out in their molecular strings.Answers can only be found by crunching through every possible solution, and most hard problems are too difficult for humans or computers to solve.

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He was looking for the one itinerary known to connect the cities in a directed Hamiltonian path - a path that would begin in Atlanta, end in Detroit, and pass through each intervening city only once.Assuming one was trying to solve the problem on a computer working at 1 trillion operations per second, this computation would take 10135 seconds - vastly longer than the age of the universe!"I didn't want to do a cheap pet trick," says Adleman of choosing this problem.Since not all cities are directly connected, the challenge lay in discovering the one continuous path to link them all.A Hamiltonian path problem involving four or five cities can be solved by doodling on a piece of paper, but when the number of cities grows by even a small amount, the problem's difficulty balloons - it becomes what is known in mathematical terms as "hard." Hard problems cannot be solved efficiently by algebraic equations.It was Christmas of 1993, and two unexpected gifts lay in front of him: a design for the world's first molecular computer, and its first problem to solve.Adleman imagined testing his DNA computer with something called a directed Hamiltonian path problem.Adleman received a bachelor’s degree (1968) in mathematics and a doctorate (1976) in computer science from the University of California, Berkeley, where his thesis adviser was Manuel Blum (the 1995 Turing Award winner).After leaving Berkeley, Adleman taught in the mathematics department at MIT (1976–80) and then in the computer science department at the University of Southern California (1980– ), where he is the Henry Salvatori Professor (1985– ) and a Distinguished Professor (2000– ).data-encryption scheme relied on the enormous difficulty of factoring the product of two very large prime numbers, which form a cryptographic key.It's a teaspoonful of DNA that's a computer! In the summer of 1993, Leonard Adleman was lying in bed reading James Watson's textbook Molecular Biology of the Gene when he mumbled to his wife, "Gee, this is really amazing stuff." And the idea hit him!Adleman, a mathematician well-known for his work in computer security and cryptography, was struck by the similarity between DNA - the basic stuff of life - and computers.


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    For DNA computing, though, the power comes from the memory capacity and parallel processing. If forced to behave sequentially, DNA loses its appeal. For example, let's look at the read and write rate of DNA. In bacteria, DNA can be replicated at a rate of about 500 base pairs a second.…

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    Jun 29, 2010. DNA computation rather DNA-based computing is at the intersection of. The church-turing thesis It states that no realizable computing.…

  • DNA computation - WRAP Warwick Research Archive Portal

    This is the first ever doctoral thesis in the field of DNA computation. The field has its roots in the late 1950s, when the Nobel laureate Richard Feynman first introduced the concept of computing at a molecular level.…

  • Parallel Computing with DNA - ch

    By another. In the last part of this thesis we extend the Domain Replacement Model to be able to design more powerful algorithms. In 2 a division algorithm for DNA computing is introduced. It bases on the Newton Method whereas we build up our algorithm from the long division. For dividing a mbit numbers it needs Ologm steps and uses Om2 DNA…

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  • Leonard Adleman - Wikipedia

    Leonard Adleman born December 31, 1945 is an American computer scientist. He is one of the creators of the RSA encryption algorithm, for which he received the 2002 Turing Award, often called the Nobel prize of Computer science. He is also known for the creation of the field of DNA computing. Thesis, Number-Theoretic Aspects of Computational Complexity 1976.…

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    DelRosso focused on DNA computing, a subfield of bionanotechnology that uses strands of DNA the same way a computer uses a microprocessor, enabling her to create a programmable biological entity.…

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    Background on DNA Computing Computers are made of physical objects and run following physical rules. For some purposes, if we ignore those objects and only focus on the mechanism of computing, the essence of a computer is only at a purely logical level. Information is transferred and logically transformed during the computing process.…

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  • Tile Self-Assembly Simulations Senior Honors Thesis

    Power of both models. This work has direct applications in DNA computing, where biologists are using these models to self-assemble pieces of DNA represented abstractly by tiles into structures at the nanoscale level. ⇤Department of Mathematics, Tufts University, Medford, MA 02155, USA, [email protected] Re-…

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