Animal experimentation is the process of testing new treatments and medicines on animals.
Computer models are not advanced enough, and testing on plants is much less applicable to humans than tests on animals such as monkeys.
Until we have a better system, we must use animal testing. Some of the tests certainly seem painful, but the great majority of people on this planet eat meat or wear leather without any guilt. Furthermore, animals clearly do not feel the same way as humans, and scientists are careful to minimize stress in the animals, since this would damage their research.
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This can be not only cruel to the animals, but also very expensive.
Animals are used in place of humans, as humans are not suitable for experiments such as these.